The FTSE 250 was down 1.77% at 20,733.03 at 1444 GMT as the war in Ukraine intensified.
Gold miner Petropavlosk – which has operations in Russia – and iron ore pellet producer Ferrexpo were heavy suffered heavy losses.
Paddy Power owner Flutter Entertainment was a big loser as it said underlying annual profit fell as the gambling group was hit by a string of punter-friendly sporting results in the UK and Ireland.
Daily Mirror publisher Reach slumped by almost a quarter after it said higher newsprint inflation would result in a drop in 2022 operating profit.
Rotork also gained even as the engineering group reported a fall in annual profits.
FTSE 250 – Risers
Rotork (ROR) 318.00p 3.05%
Centamin (DI) (CEY) 101.70p 2.52%
Darktrace (DARK) 452.20p 2.22%
BlackRock World Mining Trust (BRWM) 743.00p 2.06%
Biffa (BIFF) 331.50p 2.00%
WH Smith (SMWH) 1,656.50p 1.91%
Mediclinic International (MDC) 335.20p 1.88%
Harbour Energy (HBR) 405.20p 1.76%
Man Group (EMG) 196.05p 1.58%
Currys (CURY) 95.05p 1.22%
FTSE 250 – Fallers
Petropavlovsk (POG) 6.03p -24.63%
Reach (RCH) 171.60p -24.57%
Liontrust Asset Management (LIO) 1,372.00p -9.38%
888 Holdings (888) 220.20p -9.08%
Bridgepoint Group (Reg S) (BPT) 310.50p -8.27%
Cineworld Group (CINE) 37.10p -7.50%
easyJet (EZJ) 557.80p -7.43%
Aston Martin Lagonda Global Holdings (AML) 948.00p -7.33%
Drax Group (DRX) 654.50p -7.29%
XP Power Ltd. (DI) (XPP) 4,030.00p -7.14%




